Breast Feeding
DangerousIt is not recommended to take this medicine while breastfeeding.
Tegonat 15mg capsule is used for stomach cancer. It interferes with DNA & RNA synthesis, prevents breakdown & toxicity of 5-FU to stop the growth of cancer cells. Tegonat 15mg Capsule is a combination chemotherapy used for cancer treatment to cure stomach / gastric cancer. It icontains Tegafur, Gimeracil, & Oteraci works to stop the cancer cells to grow & multiply. The dosage and treatment schedule for Tegonat 15 mg must be determined by an oncologist based on the cancer type, body surface area, kidney function, and the overall chemotherapy regimen.. Patients with kidney, liver, blood, or breathing problems discuss with doctors before starting it.
Tegonat 15mg Capsule is a combination of Tegafur, Gimeracil & Oteracil used to treat stomach cancer. It prevents cancer cell growth. Tegafur gets converted inside the body into 5-fluorouracil (5-FU) which is an active anti-cancer substance helps to block the formation of DNA and RNA required for cancer cell growth and multiplication. Gimeracil helps in preventing the breakdown of 5-FU. Oteracil works to reduce the harmful effects of 5-FU on the stomach & intestines, which helps to decrease the gastrointestinal side effects. The combination of these medicines works to slow down & to stop the growth and spread of stomach cancer cells.
Gastric cancer occurs due to uncontrolled cell division in the lining of the stomach. It can be difficult to cure if left untreated. Tegonat 15 mg is the preferred medication when traditional chemotherapy methods are ineffective. It controls the growth of the tumor and is generally combined with other anticancer drugs for full treatment.
Colorectal cancer is one of the most commonly detected types of cancer that arises from the colon or rectum of the digestive tract. Tegonat 15 mg is used in the treatment of colorectal cancer, often in combination with other therapies. This drug is especially incorporated into treatments when the tumor has reached an advanced or metastatic stage.
Breast cancer is the most commonly detected cancer in women, especially postmenopausal women. Tegonat 15 mg is used in the treatment of breast cancers, especially those in the advanced or recurring stage. It prevents the survival and proliferation of cancer cells and is used in combination with other chemotherapy agents to enhance the effectiveness of the treatment.
Head and neck cancer affects areas like the mouth, throat, and nasal cavity. This type of cancer becomes difficult to treat once it reaches the advanced or metastatic stage. Hence, for treatment, typically additional measures like Tegonat 15 mg are used as they can control excess tumor growth and work effectively along with other anticancer treatments.
Pancreatic cancers are one of the most aggressive types of cancer. This type of cancer produces very minimal symptoms at an early stage and, hence, is generally detected very late. In such cases, Tegonat 15 mg is highly effective as it prevents the growth and spread of the cancer any further, and is sometimes used as an alternate therapy when traditional drugs are ineffective.
The dosage for Tegonat 15 mg is based on the patient’s body surface area (BSA- measured in m²). Hence, the unit of measurement for this drug is mg/m².
Tegonat 15 mg is an anticancer drug, and it is used in the treatment of various forms of cancer. It contains 15 mg of the active component, Tegafur, which helps in the prevention of the survival and growth of cancer.
Tegonat 15 mg is a prodrug, which means it is inactive until it enters the body. Once this drug enters the gastrointestinal tract, it is metabolized in the liver by cytochrome enzymes, specifically CYP2A6. Over here, it is converted into a substance called 5-Fluorouracil (5-FU). In this way, there is a slow and continuous release of the active compound 5-FU in the body.
After entering the blood circulation, 5-FU targets the cancer cells and gets converted into primary metabolites in the form of FdUMP (fluorodeoxyuridine monophosphate), FUTP, and FdUTP.
FdUMP binds to thymidylate synthase, which is involved in the formation of thymidine (a DNA nucleotide). Thymidine is one of the four main nucleic acids required for the synthesis of new DNA. FdUTP is incorporated in place of other nucleotides, which breaks the DNA strands and causes extensive damage. The FUTP molecules get incorporated into the RNA in place of uracil, which leads to the production of defective RNA molecules. As RNA is a key component in protein synthesis, damaging these molecules prevents the generation of new cellular components, ultimately leading to the arrest of cell division.
The cancer cell division is much faster and uncontrolled compared to normal cells. Hence, they are highly dependent on DNA/RNA function for survival and proliferation. This also causes the cancer cells to be highly vulnerable to biochemical agents targeting the DNA and RNA structures. Thus, by interfering with the genetic material of the cancer cells, Tegonat 15 mg disrupts the proper functioning and multiplication of the tumor.
Tegonat 15 mg works by targeting the genetic material of the cancer cells.
No. Tegonat 15 mg is a prodrug that gets converted to 5-FU after it enters the liver.
Tegonat 15 mg must be taken orally, with small doses divided across the day.
Common side effects associated with Tegonat 15 mg are nausea, vomiting, diarrhea, mouth sores, fatigue, etc.
Mild hair loss can occur, but it is usually less severe than traditional chemotherapy.
It is not recommended to take this medicine while breastfeeding.
It is unknown whether it is safe to drink alcohol while taking this medicine.
Inform your physician if you have any liver disorders before taking this medicine.
Inform your doctor about lung issues while on this medicine.
This medicine can cause tiredness. Avoid driving if you are unwell.
It is not recommended to take this medicine during pregnancy.
This medicine can be taken with food to reduce stomach irritation.
This medicine can be taken on an empty stomach for faster absorption.
